A review of preclinical animal models utilised for TB vaccine evaluation in the context of recent human efficacy data

Summary There is an urgent need for an improved TB vaccine. Vaccine development is hindered by the lack of immune correlates and uncertain predictive value of preclinical animal models. As data become available from human efficacy trials, there is an opportunity to evaluate the predictive value of t...

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Bibliographic Details
Main Authors: McShane, H, Williams, A
Format: Journal article
Language:English
Published: 2014