Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation
Long-term potentiation (LTP), a long-lasting enhancement in communication between neurons, is considered to be the major cellular mechanism underlying learning and memory. LTP triggers high-frequency calcium pulses that result in the activation of Calcium/Calmodulin (CaM)-dependent kinase II (CaMKII...
Autori principali: | Rellos, P, Pike, A, Niesen, F, Salah, E, Lee, W, Von Delft, F, Knapp, S |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
Public Library of Science
2010
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