Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation

Long-term potentiation (LTP), a long-lasting enhancement in communication between neurons, is considered to be the major cellular mechanism underlying learning and memory. LTP triggers high-frequency calcium pulses that result in the activation of Calcium/Calmodulin (CaM)-dependent kinase II (CaMKII...

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Détails bibliographiques
Auteurs principaux: Rellos, P, Pike, A, Niesen, F, Salah, E, Lee, W, Von Delft, F, Knapp, S
Format: Journal article
Langue:English
Publié: Public Library of Science 2010