Lymphotoxin-α gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study

Lymphotoxin-α (LTA) is a pro-inflammatory cytokine that plays an important role in the immune system and local inflammatory response. LTA is expressed in atherosclerotic plaques and has been implicated in the pathogenesis of atherosclerosis and coronary heart disease (CHD). Polymorphisms in the gene...

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Bibliographic Details
Main Authors: Clarke, R, Xu, P, Bennett, D, Lewington, S, Zondervan, K, Parish, S, Palmer, A, Clark, S, Cardon, L, Peto, R, Lathrop, M, Collins, R
Format: Journal article
Language:English
Published: Public Library of Science 2006