VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5.

VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5.

We have identified an ethylnitrosourea (ENU)-induced recessive mouse mutation (Vcc) with a pleiotropic phenotype that includes cardiac, tracheoesophageal, anorectal, anteroposterior patterning defects, exomphalos, hindlimb hypoplasia, a presacral mass, renal and palatal agenesis, and pulmonary hypop...

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Bibliographic Details
Main Authors: Szumska, D, Pieles, G, Essalmani, R, Bilski, M, Mesnard, D, Kaur, K, Franklyn, A, El Omari, K, Jefferis, J, Bentham, J, Taylor, J, Schneider, J, Arnold, S, Johnson, P, Tymowska-Lalanne, Z, Stammers, D, Clarke, K, Neubauer, S, Morris, A, Brown, S, Shaw-Smith, C, Cama, A, Capra, V, Ragoussis, J, Constam, D
Format: Journal article
Language:English
Published: 2008

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