Prognostic value of p53, hMLH1, hMSH2, MGMT and COX-2 in the QUASAR-1 Dukes' stage B colorectal cancer cohort

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• Prevalence of pathological germline mutations of hMLH1 and hMSH2 genes in colorectal cancer.
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  Cyhoeddwyd: (2016-08-01)
• Allele loss occurs frequently at hMLH1, but rarely at hMSH2, in sporadic colorectal cancers with microsatellite instability.
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• Differential expression of hMLH1 and hMSH2 is related to bladder cancer grade, stage and prognosis but not microsatellite instability.
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