A novel color change mechanism for breast cancer biomarker detection: naphthoquinones as specific ligands of human arylamine N-acetyltransferase 1

Human arylamine N-acetyltransferase 1 (hNAT1) has become an attractive potential biomarker for estrogen-receptor-positive breast cancers. We describe here the mechanism of action of a selective non-covalent colorimetric biosensor for the recognition of hNAT1 and its murine homologue, mNat2, over the...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Laurieri, N, Egleton, J, Varney, A, Thinnes, C, Quevedo, C, Seden, P, Thompson, S, Rodrigues-Lima, F, Dairou, J, Dupret, J, Russell, A, Sim, E
Format: Journal article
Sprache:English
Veröffentlicht: Public Library of Science 2013