Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature

Activation of cellular hypoxia pathways, orchestrated by HIF (hypoxia-inducible factor) transcription factors, is a common feature of multiple tumor types, resulting from microenvironment factors and oncogenic mutation. Although they help drive many of the “hallmarks” of cancer and are associated wi...

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Những tác giả chính: Lombardi, O, Li, R, Halim, S, Choudhry, H, Ratcliffe, PJ, Mole, DR
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Elsevier 2022