Role of STAT3 in glucocorticoid-induced expression of the human IL-10 gene.

In the present report we have determined the molecular mechanisms, which govern the expression of the human IL-10 gene when induced by the glucocorticoid Methyl-Prednisolone (MP). Treatment of cells with MP at 10(-6) M will readily induce IL-10 in CD19+ primary B cells and in a human B cell line. An...

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Bibliographic Details
Main Authors: Unterberger, C, Staples, K, Smallie, T, Williams, L, Foxwell, B, Schaefer, A, Kempkes, B, Hofer, T, Koeppel, M, Lohrum, M, Stunnenberg, H, Frankenberger, M, Ziegler-Heitbrock, L
Format: Journal article
Language:English
Published: 2008