Cardiac malformations and midline skeletal defects in mice lacking filamin A.
The X-linked gene filamin A (Flna) encodes a widely expressed actin-binding protein that crosslinks actin into orthogonal networks and interacts with a variety of other proteins including membrane proteins, integrins, transmembrane receptor complexes and second messengers, thus forming an important...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2006
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