The tetrameric plant lectin BanLec neutralizes HIV through bidentate binding to specific viral glycans.
Select lectins have powerful antiviral properties that effectively neutralize HIV-1 by targeting the dense glycan shield on the virus. Here, we reveal the mechanism by which one of the most potent lectins, BanLec, achieves its inhibition. We identify that BanLec recognises a subset of high-mannose g...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Elsevier
2017
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