The fine-scale structure of recombination rate variation in the human genome.

The nature and scale of recombination rate variation are largely unknown for most species. In humans, pedigree analysis has documented variation at the chromosomal level, and sperm studies have identified specific hotspots in which crossing-over events cluster. To address whether this picture is rep...

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Bibliographic Details
Main Authors: Mcvean, G, Myers, S, Hunt, S, Deloukas, P, Bentley, DR, Donnelly, P
Format: Journal article
Language:English
Published: 2004