TCR signal strength and T cell development
Thymocyte selection involves the positive and negative selection of the repertoire of T cell receptors (TCRs) such that the organism does not suffer autoimmunity, yet has the benefit of the ability to recognize any invading pathogen. The signal transduced through the TCR is translated into a number...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
Annual Reviews
2016
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