Genome-wide functional analysis of Plasmodium protein phosphatases reveals key regulators of parasite development and differentiation.

Reversible protein phosphorylation regulated by kinases and phosphatases controls many cellular processes. Although essential functions for the malaria parasite kinome have been reported, the roles of most protein phosphatases (PPs) during Plasmodium development are unknown. We report a functional a...

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Detalhes bibliográficos
Principais autores: Guttery, D, Poulin, B, Ramaprasad, A, Wall, R, Ferguson, D, Brady, D, Patzewitz, E, Whipple, S, Straschil, U, Wright, M, Mohamed, A, Radhakrishnan, A, Arold, S, Tate, E, Holder, A, Wickstead, B, Pain, A, Tewari, R
Formato: Journal article
Idioma:English
Publicado em: Cell Press 2014