Genome-wide functional analysis of Plasmodium protein phosphatases reveals key regulators of parasite development and differentiation.

Reversible protein phosphorylation regulated by kinases and phosphatases controls many cellular processes. Although essential functions for the malaria parasite kinome have been reported, the roles of most protein phosphatases (PPs) during Plasmodium development are unknown. We report a functional a...

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Hlavní autoři: Guttery, D, Poulin, B, Ramaprasad, A, Wall, R, Ferguson, D, Brady, D, Patzewitz, E, Whipple, S, Straschil, U, Wright, M, Mohamed, A, Radhakrishnan, A, Arold, S, Tate, E, Holder, A, Wickstead, B, Pain, A, Tewari, R
Médium: Journal article
Jazyk:English
Vydáno: Cell Press 2014