Comparison of the thermodynamic stabilities and solution conformations of DNA.RNA hybrids containing purine-rich and pyrimidine-rich strands with DNA and RNA duplexes.

The conformations and thermodynamic stabilities of duplexes containing purine-rich (GAA-GAGAAGC) and pyrimidine-rich (GCTTCTCTTC or GCUUCUCUUC) DNA and RNA strands have been measured by UV melting, electrophoresis, circular dichroism, and NMR spectroscopy. The free energies of stabilization (-delta...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Gyi, J, Conn, G, Lane, A, Brown, T
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 1996