The Childhood Acute Illness and Nutrition (CHAIN) network nested case-cohort study protocol: a multi-omics approach to understanding mortality among children in sub-Saharan Africa and South Asia

<p><strong>Introduction:</strong> Many acutely ill children in low- and middle-income settings have a high risk of mortality both during and after hospitalisation despite guideline-based care. Understanding the biological mechanisms underpinning mortality may suggest optimal pathwa...

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Main Authors: Njunge, JM, Tickell, K, Diallo, AH, Sayeem Bin Shahid, ASM, Gazi, MA, Saleem, A, Kazi, Z, Ali, S, Tigoi, C, Mupere, E, Lancioni, CL, Yoshioka, E, Chisti, MJ, Mburu, M, Ngari, M, Ngao, N, Gichuki, B, Omer, E, Gumbi, W, Singa, B, Bandsma, R, Ahmed, T, Voskuijl, W, Williams, TN, Macharia, A, Makale, J, Mitchel, A, Williams, J, Gogain, J, Janjic, N, Mandal, R, Wishart, DS, Wu, H, Xia, L, Routledge, M, Gong, YY, Espinosa, C, Aghaeepour, N, Liu, J, Houpt, E, Lawley, TD, Browne, H, Shao, Y, Rwigi, D, Kariuki, K, Kaburu, T, Uhlig, HH, Gartner, L, Jones, K, Koulman, A, Walson, J, Berkley, J
Format: Journal article
Language:English
Published: F1000Research 2022