Targeting the hypoxic tumour phenotype with T-cell immunotherapy
<p>The hypoxic tumour phenotype is a widespread phenomenon in cancers that correlates with malignant behaviour and poor clinical outcomes. The induced expression of hypoxia-regulated genes through post-translational stabilization of hypoxia-inducible factor (HIF), represent a novel class of ov...
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| Format: | Thesis |
| Language: | English |
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2004
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