Properties of multiple G.A mismatches in stable oligonucleotide duplexes.

The solution structure of the deoxydecanucleotide [sequence: see text] has been determined by NMR methods. This duplex, which contains six G.A mismatches and four Watson-Crick base pairs, is thermodynamically more stable than a decamer where T.A base pairs are substituted for the G.A mismatches, and...

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Bibliographic Details
Main Authors: Lane, A, Ebel, S, Brown, T
Format: Journal article
Language:English
Published: 1994