Properties of multiple G.A mismatches in stable oligonucleotide duplexes.

The solution structure of the deoxydecanucleotide [sequence: see text] has been determined by NMR methods. This duplex, which contains six G.A mismatches and four Watson-Crick base pairs, is thermodynamically more stable than a decamer where T.A base pairs are substituted for the G.A mismatches, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Lane, A, Ebel, S, Brown, T
Formato: Journal article
Lenguaje:English
Publicado: 1994