Selective survival of embryos can explain DNA methylation signatures of adverse prenatal environments

An adverse intrauterine environment is associated with long-term physiological changes in offspring. These are believed to be mediated by epigenomic marks, including DNA methylation (DNAm). Changes in DNAm are often interpreted as damage or plastic responses of the embryo. Here, we propose that stoc...

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Bibliografische gegevens
Hoofdauteurs: Tobi, E, van den Heuvel, J, Zwaa, B, Lumey, L, Heijmans, B, Uller, T
Formaat: Journal article
Gepubliceerd in: Cell Press 2018