Probing GPCR-Gα interactions: a functional study by EM and SPR

Probing GPCR-Gα interactions: a functional study by EM and SPR

<p>The G protein-coupled receptor (GPCR), neurotensin receptor type 1 (NTS1), is pharmacologically important and activated by the tridecapeptide hormone, neurotensin (NT), initiating a cascade of interactions through G proteins to effect cellular responses. The mechanisms by which these occur...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteur:	Adamson, RJ
Andere auteurs:	Watts, A
Formaat:	Thesis
Taal:	English
Gepubliceerd in:	2014
Onderwerpen:	Microscopy Biochemistry Biophysics Molecular biophysics (biochemistry) Membrane proteins Biosensors Protein chemistry Nano-biotechnology

Gelijkaardige items

Bioelectrochemistry by fluorescent cyclic voltammetry
door: Mizzon, G
Gepubliceerd in: (2012)

Single-molecule DNA sensors and cages for transcription factors in vitro and in vivo
door: Crawford, R
Gepubliceerd in: (2011)

The influence of environment: simulations of the influenza BM2 proton channel
door: Rouse, S
Gepubliceerd in: (2012)

Structural studies of integrin activation
door: Anthis, N, et al.
Gepubliceerd in: (2009)

Single molecule studies of a voltage-gated potassium channel
door: Angué, L
Gepubliceerd in: (2013)

Computational studies of ligand-water mediated interactions in ionotropic glutamate receptors
door: Sahai, M
Gepubliceerd in: (2011)

Structure and function of bacterial proteins secreted by the type three secretion and twin arginine translocation pathways
door: Lillington, J, et al.
Gepubliceerd in: (2011)

Protocol for real-time imaging of membrane fission by mitofissin
door: Tatsuro Maruyama, et al.
Gepubliceerd in: (2023-12-01)

Structural studies of cell surface signalling molecules for neuronal guidance and connectivity
door: Mitakidis, N
Gepubliceerd in: (2013)

Imaging the assembly of the Staphylococcal pore-forming toxin alpha-Hemolysin
door: Thompson, J, et al.
Gepubliceerd in: (2009)

Engineered α-hemolysin pores with chemically and genetically-fused functional proteins
door: Mantri, S
Gepubliceerd in: (2013)

Engineered α-hemolysin pores with chemically and genetically-fused functional proteins
door: Mantri, S
Gepubliceerd in: (2013)

Biophysical characterisation of self-assembling nanoparticles
door: Sawczyc, HLD
Gepubliceerd in: (2020)

Protocol for evaluating drug-protein interactions based on fluorescence spectroscopy
door: Elaheh Jalali, et al.
Gepubliceerd in: (2024-12-01)

Optimising protein synthesis in cell‐free systems, a review
door: Angelo C. Batista, et al.
Gepubliceerd in: (2021-03-01)

Studying marcomolecular transitions by NMR and computer simulations
door: Stelzl, LS
Gepubliceerd in: (2014)

Pushing the boundaries: molecular dynamics simulations of complex biological membranes
door: Parton, D
Gepubliceerd in: (2011)

Activation of a diluted E. coli cell-free transcription-translation system within liposomes by hypertonic concentration
door: Yukino Matsui, et al.
Gepubliceerd in: (2021-12-01)

Mechanism of SigR inhibition by the anti-sigma factor RsrA from Streptomyces coelicolor
door: Francis, M, et al.
Gepubliceerd in: (2015)

Interactions of Neisseria meningitidis with the human immune system
door: Harding, R
Gepubliceerd in: (2015)

DNA origami assembly
door: Dunn, K, et al.
Gepubliceerd in: (2014)

Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues
door: Labro, A, et al.
Gepubliceerd in: (2008)

Molecular dissection of ionotropic glutamate receptor delta-family interactions with trans-synaptic proteins
door: Clay, J, et al.
Gepubliceerd in: (2013)

Fluorescence studies of influenza RNA and RNA polymerase
door: Tomescu, A
Gepubliceerd in: (2014)

A biophysical study of the G protein coupled receptor neurotensin receptor 1
door: Harding, PJ
Gepubliceerd in: (2007)

Improving rapid affinity calculations for drug-protein interactions
door: Ross, G
Gepubliceerd in: (2013)

Molecular characterisation of bacterial proteins that interact with sulfur or nitrogen compounds
door: Grabarczyk, D, et al.
Gepubliceerd in: (2014)

Probing sulfatide-tissue lectin recognition with functionalized glycodendrimersomes
door: Paul V. Murphy, et al.
Gepubliceerd in: (2021-01-01)

Site-specific phosphorylation of PSD-95 dynamically regulates the postsynaptic density as observed by phase separation
door: Maria Vistrup-Parry, et al.
Gepubliceerd in: (2021-11-01)

Molecular and structural characterisation of the human Fibrillin-1 N-C terminal interaction
door: Yadin, D
Gepubliceerd in: (2013)

Biophysical studies of membrane protein structure and function
door: Dijkman, P, et al.
Gepubliceerd in: (2014)

Molecular dynamics study of water and Na⁺ ions in models of the pore region of the nicotinic acetylcholine receptor
door: Smith, G, et al.
Gepubliceerd in: (1997)

The regulation and inhibition of P-TEFb
door: Hole, A
Gepubliceerd in: (2011)

Structural studies of a membrane embedded chloride channel from E.Coli, a prokaryotic homologue of ClC channels
door: Bowler, M, et al.
Gepubliceerd in: (2001)

Radiation damage in protein crystals examined under various conditions by different methods
door: Garman, E, et al.
Gepubliceerd in: (2009)

Biophysical and magnetic resonance studies of membrane proteins
door: Orwick, M, et al.
Gepubliceerd in: (2011)

Determination of X-ray flux using silicon pin diodes
door: Owen, R, et al.
Gepubliceerd in: (2009)

Monitoring GPCR conformation with GFP-inspired dyes
door: Anatoliy Belousov, et al.
Gepubliceerd in: (2024-08-01)

An optogenetic proximity labeling approach to probe the composition of inducible biomolecular condensates in cultured cells
door: Emile Alghoul, et al.
Gepubliceerd in: (2021-09-01)

Gαs slow conformational transition upon GTP binding and a novel Gαs regulator
door: Donghoon Ahn, et al.
Gepubliceerd in: (2023-05-01)