Structural and mechanistic basis of penicillin-binding protein inhibition by lactivicins.
Beta-lactam antibiotics, including penicillins and cephalosporins, inhibit penicillin-binding proteins (PBPs), which are essential for bacterial cell wall biogenesis. Pathogenic bacteria have evolved efficient antibiotic resistance mechanisms that, in Gram-positive bacteria, include mutations to PBP...
Egile Nagusiak: | Macheboeuf, P, Fischer, D, Brown, T, Zervosen, A, Luxen, A, Joris, B, Dessen, A, Schofield, C |
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Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
2007
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Antzeko izenburuak
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MEDI 327-Structural and mechanistic basis of penicillin-binding protein inhibition by lactivicins
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