A common functional polymorphism in the promoter region of the microsomal triglyceride transfer protein gene influences plasma LDL levels.

A common functional polymorphism in the promoter region of the microsomal triglyceride transfer protein gene influences plasma LDL levels.

Microsomal triglyceride transfer protein (MTP) is required for the assembly and cellular secretion of apolipoprotein B (apoB) -containing lipoproteins from the liver and intestine. The secretion pattern of apoB-containing lipoproteins is likely to influence the VLDL and LDL levels in plasma. By init...

Ամբողջական նկարագրություն

Մատենագիտական մանրամասներ
Հիմնական հեղինակներ:	Karpe, F, Lundahl, B, Ehrenborg, E, Eriksson, P, Hamsten, A
Ձևաչափ:	Journal article
Լեզու:	English
Հրապարակվել է:	1998

Նմանատիպ նյութեր

Functional studies of a common promoter polymorphism in the microsomal triglyceride transfer protein gene (MTP)
‌: Ehrenborg, E, և այլն
Հրապարակվել է: (1999)

Postprandial plasma ApoB-48 levels are influenced by a polymorphism in the promoter of the microsomal triglyceride transfer protein gene.
‌: Lundahl, B, և այլն
Հրապարակվել է: (2002)

A common functional polymorphism in the promoter region of the MTP gene influences the plasma LDL level
‌: Karpe, F, և այլն
Հրապարակվել է: (1998)

Microsomal triglyceride transfer protein -493T variant reduces IDL plus LDL apoB production and the plasma concentration of large LDL particles.
‌: Lundahl, B, և այլն
Հրապարակվել է: (2006)

A functional polymorphism in the promoter region of the microsomal triglyceride transfer protein (MTP -493G/T) influences lipoprotein phenotype in familial hypercholesterolemia.
‌: Björn Lundahl, և այլն
Հրապարակվել է: (2000)

The effect of six polymorphisms in the microsomal triglyceride transfer protein (MTP) gene on distribution of LDL subtractions in healthy middle-aged men
‌: Andersson, C, և այլն
Հրապարակվել է: (2000)

Variants of the microsomal triglyceride transfer protein gene are associated with plasma cholesterol levels and body mass index.
‌: Ledmyr, H, և այլն
Հրապարակվել է: (2002)

Variants of the microsomal triglyceride transfer protein gene are associated with plasma cholesterol levels and body mass index
‌: Helena Ledmyr, և այլն
Հրապարակվել է: (2002-01-01)

Common variants in genes encoding plasma lipid-transfer and lipolytic proteins are associated with increased LDL particle size
‌: Andersson, C, և այլն
Հրապարակվել է: (2002)

The Ile128Thr polymorphism influences stability and ligand binding properties of the microsomal triglyceride transfer protein
‌: H. Ledmyr, և այլն
Հրապարակվել է: (2006-07-01)

The microsomal triglyceride transfer protein-493T allele confers increased risk of coronary heart disease
‌: Ledmyr, H, և այլն
Հրապարակվել է: (2002)

JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs
‌: Shrestha Sudeep, և այլն
Հրապարակվել է: (2005-09-01)

The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease.
‌: Ledmyr, H, և այլն
Հրապարակվել է: (2004)

Multiple functions of microsomal triglyceride transfer protein
‌: Hussain M Mahmood, և այլն
Հրապարակվել է: (2012-02-01)

Subcellular localization of microsomal triglyceride transfer protein
‌: Larry L. Swift, և այլն
Հրապարակվել է: (2003-10-01)

Identification of two polymorphisms in the promoter of the microsomal triglyceride transfer protein (MTP) gene: lack of association with lipoprotein profiles
‌: Stefan-Martin Herrmann, և այլն
Հրապարակվել է: (1998-12-01)

Loss of both phospholipid and triglyceride transfer activities of microsomal triglyceride transfer protein in abetalipoproteinemia
‌: Irani Khatun, և այլն
Հրապարակվել է: (2013-06-01)

A common promoter polymorphism affecting transcription of the MTP-gene influences lipoprotein phenotype in familial hypercholesterolaemia
‌: Lundahl, B, և այլն
Հրապարակվել է: (1998)

Intestinal fatty acid binding protein and microsomal triglyceride transfer protein polymorphisms in French-Canadian youth
‌: Simona Stan, և այլն
Հրապարակվել է: (2005-02-01)

Microsomal triglyceride transfer protein expression during mouse development
‌: John M. Shelton, և այլն
Հրապարակվել է: (2000-04-01)

Remnant lipoproteins are related to intima-media thickness of the carotid artery independently of LDL cholesterol and plasma triglycerides.
‌: Karpe, F, և այլն
Հրապարակվել է: (2001)

Effects of native, triglyceride-enriched, and oxidatively modified LDL on plasminogen activator inhibitor-1 expression in human endothelial cells.
‌: Allison, B, և այլն
Հրապարակվել է: (1999)

Remnant lipoproteins are related to intima-media thickness of the carotid artery independently of LDL cholesterol and plasma triglycerides
‌: Fredrik Karpe, և այլն
Հրապարակվել է: (2001-01-01)

Microsomal triglyceride transfer protein contributes to lipid droplet maturation in adipocytes.
‌: Larry L Swift, և այլն
Հրապարակվել է: (2017-01-01)

Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein
‌: Narasimha Anaganti, և այլն
Հրապարակվել է: (2022-09-01)

Novel mutations in the microsomal triglyceride transfer protein gene causing abetalipoproteinemia
‌: Ken Ohashi, և այլն
Հրապարակվել է: (2000-08-01)

A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein.
‌: Meredith H Wilson, և այլն
Հրապարակվել է: (2020-08-01)

Transfer of cholesteryl esters and phospholipids as well as net deposition by microsomal triglyceride transfer protein
‌: Paul Rava, և այլն
Հրապարակվել է: (2005-08-01)

Influence of common variants in the CETP, LPL, HL and APO E genes on LDL heterogeneity in healthy, middle-aged men.
‌: Skoglund-Andersson, C, և այլն
Հրապարակվել է: (2003)

Cardiac expression of microsomal triglyceride transfer protein is increased in obesity and serves to attenuate cardiac triglyceride accumulation.
‌: Emil D Bartels, և այլն
Հրապարակվել է: (2009-01-01)

An improved assay to measure the phospholipid transfer activity of microsomal triglyceride transport protein
‌: Narasimha Anaganti, և այլն
Հրապարակվել է: (2021-01-01)

Identification of a Novel Transcript and Regulatory Mechanism for Microsomal Triglyceride Transfer Protein.
‌: Takashi Suzuki, և այլն
Հրապարակվել է: (2016-01-01)

Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly
‌: M.Mahmood Hussain, և այլն
Հրապարակվել է: (2003-01-01)

Retina expresses microsomal triglyceride transfer protein: implications for age-related maculopathy
‌: Chuan-Ming Li, և այլն
Հրապարակվել է: (2005-04-01)

A simple, rapid, and sensitive fluorescence assay for microsomal triglyceride transfer protein
‌: Humra Athar, և այլն
Հրապարակվել է: (2004-04-01)

Microsomal triglyceride transfer protein in the ectoparasitic crustacean salmon louse (Lepeophtheirus salmonis)
‌: Muhammad Tanveer Khan, և այլն
Հրապարակվել է: (2017-08-01)

Microsomal triglyceride transfer protein in CaCo-2 cells: characterization and regulation.
‌: S N Mathur, և այլն
Հրապարակվել է: (1997-01-01)

Regulation of microsomal triglyceride transfer protein mRNA expression by endotoxin and cytokines
‌: Miguel Navasa, և այլն
Հրապարակվել է: (1998-06-01)

Common polymorphisms in the factor VII gene locus influence the basal and postprandial plasma concentrations of activated factor VII
‌: Silveira, A, և այլն
Հրապարակվել է: (1999)

Microsomal triglyceride transfer protein is essential for hepatic secretion of apoB-100 and apoB-48 but not triglyceride
‌: To Yuen Hui, և այլն
Հրապարակվել է: (2002-05-01)