Falciparum malaria mortality in sub-Saharan Africa in the pretreatment era
Driven by the malaria-protective effect of sickle-cell trait, balancing selection results in hemoglobin S equilibrium allele frequencies of between 15% and 20% in areas of high <i>Plasmodium falciparum</i> transmission in sub-Saharan Africa. From this we estimate that the malaria-attribu...
Main Authors: | , , |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
Cell Press
2021
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