Falciparum malaria mortality in sub-Saharan Africa in the pretreatment era
Driven by the malaria-protective effect of sickle-cell trait, balancing selection results in hemoglobin S equilibrium allele frequencies of between 15% and 20% in areas of high <i>Plasmodium falciparum</i> transmission in sub-Saharan Africa. From this we estimate that the malaria-attribu...
| Main Authors: | , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Cell Press
2021
|