Falciparum malaria mortality in sub-Saharan Africa in the pretreatment era
Driven by the malaria-protective effect of sickle-cell trait, balancing selection results in hemoglobin S equilibrium allele frequencies of between 15% and 20% in areas of high <i>Plasmodium falciparum</i> transmission in sub-Saharan Africa. From this we estimate that the malaria-attribu...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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Cell Press
2021
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| _version_ | 1797111535373385728 |
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| author | Watson, JA White, NJ Dondorp, AM |
| author_facet | Watson, JA White, NJ Dondorp, AM |
| author_sort | Watson, JA |
| collection | OXFORD |
| description | Driven by the malaria-protective effect of sickle-cell trait, balancing selection results in hemoglobin S equilibrium allele frequencies of between 15% and 20% in areas of high <i>Plasmodium falciparum</i> transmission in sub-Saharan Africa. From this we estimate that the malaria-attributable childhood mortality in the pretreatment era was between 15% and 24%. |
| first_indexed | 2024-03-07T08:11:41Z |
| format | Journal article |
| id | oxford-uuid:d26e3a7d-79b3-427d-bc7e-38866e8a9e1e |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T08:11:41Z |
| publishDate | 2021 |
| publisher | Cell Press |
| record_format | dspace |
| spelling | oxford-uuid:d26e3a7d-79b3-427d-bc7e-38866e8a9e1e2023-11-24T10:45:54ZFalciparum malaria mortality in sub-Saharan Africa in the pretreatment eraJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d26e3a7d-79b3-427d-bc7e-38866e8a9e1eEnglishSymplectic ElementsCell Press2021Watson, JAWhite, NJDondorp, AMDriven by the malaria-protective effect of sickle-cell trait, balancing selection results in hemoglobin S equilibrium allele frequencies of between 15% and 20% in areas of high <i>Plasmodium falciparum</i> transmission in sub-Saharan Africa. From this we estimate that the malaria-attributable childhood mortality in the pretreatment era was between 15% and 24%. |
| spellingShingle | Watson, JA White, NJ Dondorp, AM Falciparum malaria mortality in sub-Saharan Africa in the pretreatment era |
| title | Falciparum malaria mortality in sub-Saharan Africa in the pretreatment era |
| title_full | Falciparum malaria mortality in sub-Saharan Africa in the pretreatment era |
| title_fullStr | Falciparum malaria mortality in sub-Saharan Africa in the pretreatment era |
| title_full_unstemmed | Falciparum malaria mortality in sub-Saharan Africa in the pretreatment era |
| title_short | Falciparum malaria mortality in sub-Saharan Africa in the pretreatment era |
| title_sort | falciparum malaria mortality in sub saharan africa in the pretreatment era |
| work_keys_str_mv | AT watsonja falciparummalariamortalityinsubsaharanafricainthepretreatmentera AT whitenj falciparummalariamortalityinsubsaharanafricainthepretreatmentera AT dondorpam falciparummalariamortalityinsubsaharanafricainthepretreatmentera |