Ring-closing metathesis: novel routes to aromatic heterocycles.

Olefin metathesis has been established as an important and general reaction in synthetic organic chemistry. Recently, it has attracted interest as a powerful tool for the construction of aromatic heterocycles. The importance of heteroaromatic motifs in medicinal chemistry and biology, as well as the...

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Detalhes bibliográficos
Main Authors: Donohoe, T, Fishlock, L, Procopiou, P
Formato: Journal article
Idioma:English
Publicado em: 2008
Descrição
Resumo:Olefin metathesis has been established as an important and general reaction in synthetic organic chemistry. Recently, it has attracted interest as a powerful tool for the construction of aromatic heterocycles. The importance of heteroaromatic motifs in medicinal chemistry and biology, as well as the efficiency and wealth of metathesis transformations, have resulted in significant success in this rapidly developing area.