MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress

The partner and localiser of BRCA2 (PALB2) plays important roles in the maintenance of genome integrity and protection against cancer. Although PALB2 is commonly described as a repair factor recruited to sites of DNA breaks, recent studies provide evidence that PALB2 also associates with unperturbed...

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Bibliographic Details
Main Authors: Bleuyard, J, Fournier, M, Nakato, R, Couturier, A, Katou, Y, Ralf, C, Hester, S, Dominguez, D, Rhodes, D, Humphrey, T, Shirahige, K, Esashi, F
Format: Journal article
Language:English
Published: National Academy of Sciences 2017