Therapeutic targeting of histone H3 lysine 36 trimethylation-deficient cancers

Therapeutic targeting of histone H3 lysine 36 trimethylation-deficient cancers

<p>Histone modifications play diverse and essential roles in the maintenance of genome integrity, as evidenced by the frequency at which different histone marks are dysregulated during tumourigenesis. The trimethylation of histone H3 at lysine 36 (H3K36me3) and SETD2, the enzyme solely respons...

Полное описание

Библиографические подробности
Главный автор:	Lopez, K
Другие авторы:	Humphrey, T
Формат:	Диссертация
Язык:	English
Опубликовано:	2019
Предметы:	Oncology

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