Th17 cells induce a distinct graft rejection response that does not require IL-17A

IL-17A-producing helper T (Th17) cells have been implicated in the pathogenesis of autoimmune disease, inflammatory bowel disease and graft rejection, however the mechanisms by which they cause tissue damage remain ill-defined. We examined what damage Th17 cell lines could inflict on allogeneic skin...

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Bibliographic Details
Main Authors: Agorogiannis, E, Regateiro, F, Howie, D, Waldmann, H, Cobbold, S
Format: Journal article
Published: 2012