The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths.

We have studied the role of carbonic anhydrase 9 (CA9), a cancer-associated extracellular isoform of the enzyme carbonic anhydrase in multicellular spheroid growths (radius of approximately 300 microm) of human colon carcinoma HCT116 cells. Spheroids were transfected with CA9 (or empty vector) and i...

詳細記述

書誌詳細
主要な著者: Swietach, P, Patiar, S, Supuran, C, Harris, A, Vaughan-Jones, R
フォーマット: Journal article
言語:English
出版事項: 2009