A comparison of case-control and family-based association methods: the example of sickle-cell and malaria.
There has been much debate about the relative merits of population- and family-based strategies for testing genetic association, yet there is little empirical data that directly compare the two approaches. Here we compare case-control and transmission/disequilibrium test (TDT) study designs using a...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2005
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