A comparison of case-control and family-based association methods: the example of sickle-cell and malaria.

There has been much debate about the relative merits of population- and family-based strategies for testing genetic association, yet there is little empirical data that directly compare the two approaches. Here we compare case-control and transmission/disequilibrium test (TDT) study designs using a...

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Bibliographic Details
Main Authors: Ackerman, H, Usen, S, Jallow, M, Sisay-Joof, F, Pinder, M, Kwiatkowski, D
Format: Journal article
Language:English
Published: 2005