Gag-specific CD4+ T-cell responses are associated with virological control of paediatric HIV-1 infection

HIV-specific Elispot responses were investigated in 57 antiretroviral therapy-naïve children, of median age 9.9 years. CD8+ T-cell responses were detected in 96% children; Nef was the immunodominant protein. Responses broadened over time but there was no association between magnitude, breadth or spe...

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Bibliographic Details
Main Authors: Prendergast, A, Goodliffe, H, Clapson, M, Cross, R, Tudor-Williams, G, Riddell, A, Daniels, J, Williams, A, Goulder, P
Format: Journal article
Published: Lippincott, Williams and Wilkins 2011