Modulation of cancer-specific immune responses by amino acid degrading enzymes.
To evade immune destruction, tumours exploit a wide range of immune escape mechanisms, including the induction of an immunosuppressive tumour microenvironment. This is mediated, in part, by amino acid-degrading enzymes indoleamine 2,3-dioxygenase, tryptophan 2,3-dioxygenase, arginase 1 and arginase...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Future Medicine
2016
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