Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression.

BACKGROUND AND PURPOSE: In muscle-invasive bladder cancer there is an urgent need to identify relatively non-toxic radiosensitising agents for use in elderly patients. Histone deacetylase inhibitors radiosensitise tumour cells but not normal cells in vitro and variously downregulate DNA damage signa...

詳細記述

書誌詳細
主要な著者: Groselj, B, Kerr, M, Kiltie, A
フォーマット: Journal article
言語:English
出版事項: 2013