Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression.

BACKGROUND AND PURPOSE: In muscle-invasive bladder cancer there is an urgent need to identify relatively non-toxic radiosensitising agents for use in elderly patients. Histone deacetylase inhibitors radiosensitise tumour cells but not normal cells in vitro and variously downregulate DNA damage signa...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Groselj, B, Kerr, M, Kiltie, A
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2013