Antibodies from malaria-exposed Malians generally interact additively or synergistically with human vaccine-induced RH5 antibodies

Reticulocyte-binding protein homolog 5 (RH5) is a leading <i>Plasmodium falciparum</i> blood-stage vaccine candidate. Another possible candidate, apical membrane antigen 1 (AMA1), was not efficacious in malaria-endemic populations, likely due to pre-existing antimalarial antibodies that...

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Bibliographic Details
Main Authors: Willcox, AC, Huber, AS, Diouf, A, Barrett, JR, Silk, SE, Pulido, D, King, LDW, Alanine, DGW, Minassian, AM, Diakite, M, Draper, SJ, Long, CA, Miura, K
Format: Journal article
Language:English
Published: Cell Press 2021