Malaria exposure drives both cognate and bystander human B cells to adopt an atypical phenotype

Atypical memory B cells (aMBCs) are found in elevated numbers in individuals exposed to malaria. A key question is whether malaria induces aMBCs as a result of exposure to Ag, or non-Ag-specific mechanisms. We identified Plasmodium and bystander tetanus toxoid (TT) specific B cells in individuals fr...

Full description

Bibliographic Details
Main Authors: Aye, R, Sutton, HJ, Nduati, EW, Kai, O, Mwacharo, J, Musyoki, J, Otieno, E, Wambua, J, Bejon, P, Cockburn, IA, Ndungu, FM
Format: Journal article
Language:English
Published: Wiley 2020