Malaria exposure drives both cognate and bystander human B cells to adopt an atypical phenotype

Atypical memory B cells (aMBCs) are found in elevated numbers in individuals exposed to malaria. A key question is whether malaria induces aMBCs as a result of exposure to Ag, or non-Ag-specific mechanisms. We identified Plasmodium and bystander tetanus toxoid (TT) specific B cells in individuals fr...

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Main Authors: Aye, R, Sutton, HJ, Nduati, EW, Kai, O, Mwacharo, J, Musyoki, J, Otieno, E, Wambua, J, Bejon, P, Cockburn, IA, Ndungu, FM
格式: Journal article
語言:English
出版: Wiley 2020