Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene.

BACKGROUND: There is a need to develop robust and clinically applicable gene expression signatures. Hypoxia is a key factor promoting solid tumour progression and resistance to therapy; a hypoxia signature has the potential to be not only prognostic but also to predict benefit from particular inter...

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Bibliographic Details
Main Authors: Buffa, F, Harris, A, West, C, Miller, C
Format: Journal article
Language:English
Published: 2010