Parameter-free model discrimination criterion based on steady-state coplanarity.

We introduce a procedure for deciding when a mass-action model is incompatible with observed steady-state data that does not require any parameter estimation. Thus, we avoid the difficulties of nonlinear optimization typically associated with methods based on parameter fitting. Instead, we borrow id...

Full description

Bibliographic Details
Main Authors: Harrington, H, Ho, K, Thorne, T, Stumpf, M
Format: Journal article
Language:English
Published: 2012