Parameter-free model discrimination criterion based on steady-state coplanarity.

We introduce a procedure for deciding when a mass-action model is incompatible with observed steady-state data that does not require any parameter estimation. Thus, we avoid the difficulties of nonlinear optimization typically associated with methods based on parameter fitting. Instead, we borrow id...

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Autori principali: Harrington, H, Ho, K, Thorne, T, Stumpf, M
Natura: Journal article
Lingua:English
Pubblicazione: 2012