Transcriptional derepression of the ERVWE1 locus following influenza A virus infection.

UNLABELLED: Syncytin-1, a fusogenic protein encoded by a human endogenous retrovirus of the W family (HERV-W) element (ERVWE1), is expressed in the syncytiotrophoblast layer of the placenta. This locus is transcriptionally repressed in adult tissues through promoter CpG methylation and suppressive h...

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Bibliographic Details
Main Authors: Li, F, Nellåker, C, Sabunciyan, S, Yolken, R, Jones-Brando, L, Johansson, A, Owe-Larsson, B, Karlsson, H
Format: Journal article
Language:English
Published: American Society for Microbiology 2014