Single-molecule FRET studies on the cotranscriptional folding of a thiamine pyrophosphate riboswitch

Because RNAs fold as they are being synthesized, their transcription rate can affect their folding. Here, we report the results of single-molecule fluorescence studies that characterize the ligand-dependent cotranscriptional folding of the Escherichia coli thiM riboswitch that regulates translation....

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Bibliographic Details
Main Authors: Uhm, H, Kang, W, Ha, K, Kang, C, Hohng, S
Format: Journal article
Language:English
Published: National Academy of Sciences 2017