Live cell imaging reveals distinct roles in cell cycle regulation for Nek2A and Nek2B.

Two splice variants of Nek2 kinase, a member of the NIMA-related family, have been identified as Nek2A and Nek2B. Nek2A regulates centrosome disjunction, spindle formation checkpoint signaling, and faithful chromosome segregation. A specific role for Nek2B has not yet been identified. Here, we have...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Fletcher, L, Cerniglia, G, Yen, T, Muschel, R
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2005