Pitfalls in estimating piperaquine elimination.
By using a sensitive new assay, the terminal elimination half-life of the antimalarial piperaquine in a healthy volunteer was estimated to be 33 days, which is longer than estimated previously. This result illustrates the importance of extended sampling duration and sensitive assay methodologies in...
Hauptverfasser: | Tarning, J, Lindegårdh, N, Annerberg, A, Singtoroj, T, Day, N, Ashton, M, White, N |
---|---|
Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2005
|
Ähnliche Einträge
Ähnliche Einträge
-
Development and validation of an automated solid phase extraction and liquid chromatographic method for the determination of piperaquine in urine.
von: Tarning, J, et al.
Veröffentlicht: (2006) -
Pharmacokinetic evaluation and metabolite characterization of the antimalarial piperaquine in the rat
von: Tarning, J, et al.
Veröffentlicht: (2007) -
Pharmacokinetics and metabolism of the antimalarial piperaquine after intravenous and oral single doses to the rat.
von: Tarning, J, et al.
Veröffentlicht: (2008) -
Characterization of human urinary metabolites of the antimalarial piperaquine.
von: Tarning, J, et al.
Veröffentlicht: (2006) -
Population pharmacokinetic assessment of the effect of food on piperaquine bioavailability in patients with uncomplicated malaria.
von: Tarning, J, et al.
Veröffentlicht: (2014)