Pitfalls in estimating piperaquine elimination.

Pitfalls in estimating piperaquine elimination.

By using a sensitive new assay, the terminal elimination half-life of the antimalarial piperaquine in a healthy volunteer was estimated to be 33 days, which is longer than estimated previously. This result illustrates the importance of extended sampling duration and sensitive assay methodologies in...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Tarning, J, Lindegårdh, N, Annerberg, A, Singtoroj, T, Day, N, Ashton, M, White, N
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2005

समान संसाधन

Development and validation of an automated solid phase extraction and liquid chromatographic method for the determination of piperaquine in urine.
द्वारा: Tarning, J, और अन्य
प्रकाशित: (2006)

Pharmacokinetic evaluation and metabolite characterization of the antimalarial piperaquine in the rat
द्वारा: Tarning, J, और अन्य
प्रकाशित: (2007)

Pharmacokinetics and metabolism of the antimalarial piperaquine after intravenous and oral single doses to the rat.
द्वारा: Tarning, J, और अन्य
प्रकाशित: (2008)

Characterization of human urinary metabolites of the antimalarial piperaquine.
द्वारा: Tarning, J, और अन्य
प्रकाशित: (2006)

Population pharmacokinetic assessment of the effect of food on piperaquine bioavailability in patients with uncomplicated malaria.
द्वारा: Tarning, J, और अन्य
प्रकाशित: (2014)

A new approach to evaluate regression models during validation of bioanalytical assays.
द्वारा: Singtoroj, T, और अन्य
प्रकाशित: (2006)

A new approach to evaluate regression models during validation of bioanalytical assays
द्वारा: Singtoroj, T, और अन्य
प्रकाशित: (2006)

Quantification of the antimalarial piperaquine in plasma.
द्वारा: Tarning, J, और अन्य
प्रकाशित: (2008)

A small amount of fat does not affect piperaquine exposure in patients with malaria.
द्वारा: Annerberg, A, और अन्य
प्रकाशित: (2011)

A small amount of fat does not affect piperaquine exposure in patients with malaria.
द्वारा: Annerberg, A, और अन्य
प्रकाशित: (2011)

Population pharmacokinetics of piperaquine after two different treatment regimens of dihydroartemisinin piperaquine in patients with acute uncomplicated falciparum malaria in Thailand
द्वारा: Tarning, J, और अन्य
प्रकाशित: (2007)

Population pharmacokinetics of piperaquine after two different treatment regimens with dihydroartemisinin-piperaquine in patients with Plasmodium falciparum malaria in Thailand.
द्वारा: Tarning, J, और अन्य
प्रकाशित: (2008)

Development and validation of a liquid chromatographic-tandem mass spectrometric method for determination of piperaquine in plasma stable isotope labeled internal standard does not always compensate for matrix effects.
द्वारा: Lindegardh, N, और अन्य
प्रकाशित: (2008)

Comparison of plasma, venous and capillary blood levels of piperaquine in patients with uncomplicated falciparum malaria.
द्वारा: Ashley, E, और अन्य
प्रकाशित: (2010)

Comparison of plasma, venous and capillary blood levels of piperaquine in patients with uncomplicated falciparum malaria
द्वारा: Ashley, E, और अन्य
प्रकाशित: (2010)

A population pharmacokinetic model of piperaquine in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum malaria in Sudan.
द्वारा: Hoglund, R, और अन्य
प्रकाशित: (2012)

Population pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated malaria.
द्वारा: Tarning, J, और अन्य
प्रकाशित: (2012)

Population Pharmacokinetics of Dihydroartemisinin and Piperaquine in Pregnant and Nonpregnant Women with Uncomplicated Malaria
द्वारा: Tarning, J, और अन्य
प्रकाशित: (2012)

Population pharmacokinetics and pharmacodynamics of piperaquine in children with uncomplicated falciparum malaria.
द्वारा: Tarning, J, और अन्य
प्रकाशित: (2012)

Population pharmacokinetics and pharmacodynamics of piperaquine in children with uncomplicated falciparum malaria
द्वारा: Tarning, J, और अन्य
प्रकाशित: (2012)

Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine
द्वारा: Zongo, I, और अन्य
प्रकाशित: (2014)

Identification of an isomer impurity in piperaquine drug substance.
द्वारा: Lindegårdh, N, और अन्य
प्रकाशित: (2006)

Automated solid-phase extraction method for the determination of piperaquine in whole blood by rapid liquid chromatography.
द्वारा: Lindegårdh, N, और अन्य
प्रकाशित: (2003)

Automated solid-phase extraction method for the determination of piperaquine in plasma by peak compression liquid chromatography.
द्वारा: Lindegårdh, N, और अन्य
प्रकाशित: (2003)

Pharmacokinetics of piperaquine in pregnant women in Sudan with uncomplicated Plasmodium falciparum malaria.
द्वारा: Adam, I, और अन्य
प्रकाशित: (2012)

A population pharmacokinetic model of piperaquine in pregnant and non-pregnant women with uncomplicated <it>Plasmodium falciparum</it> malaria in Sudan
द्वारा: Hoglund Richard M, और अन्य
प्रकाशित: (2012-11-01)

Pharmacokinetics of piperaquine in pregnant women in Sudan with uncomplicated Plasmodium falciparum malaria
द्वारा: Adam, I, और अन्य
प्रकाशित: (2012)

Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison.
द्वारा: Smithuis, F, और अन्य
प्रकाशित: (2006)

Pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated falciparum malaria.
द्वारा: Rijken, M, और अन्य
प्रकाशित: (2011)

Development and validation of a solid-phase extraction-liquid chromatographic method for determination of amoxicillin in plasma.
द्वारा: Lindeg?rdh, N, और अन्य
प्रकाशित: (2005)

Population pharmacokinetics and electrocardiographic effects of dihydroartemisinin-piperaquine in healthy volunteers
द्वारा: Chotsiri, P, और अन्य
प्रकाशित: (2017)

Efficacy and safety of dihydroartemisinin-piperaquine.
द्वारा: Myint, H, और अन्य
प्रकाशित: (2007)

High throughput assay for the determination of piperaquine in plasma.
द्वारा: Lindeg?rdh, N, और अन्य
प्रकाशित: (2005)

Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine.
द्वारा: Issaka Zongo, और अन्य
प्रकाशित: (2014-01-01)

Prediction of improved antimalarial chemoprevention with weekly dosing of dihydroartemisinin-piperaquine.
द्वारा: Permala, J, और अन्य
प्रकाशित: (2017)

Population Pharmacokinetics and Antimalarial Pharmacodynamics of Piperaquine in Patients With Plasmodium vivax Malaria in Thailand.
द्वारा: Tarning, J, और अन्य
प्रकाशित: (2014)

Population pharmacokinetics and antimalarial pharmacodynamics of piperaquine in patients with plasmodium vivax malaria in Thailand
द्वारा: Tarning, J, और अन्य
प्रकाशित: (2014)

Characterization of an in vivo concentration-effect relationship for piperaquine in malaria chemoprevention.
द्वारा: Bergstrand, M, और अन्य
प्रकाशित: (2014)

High throughput assay for the determination of lumefantrine in plasma.
द्वारा: Annerberg, A, और अन्य
प्रकाशित: (2005)

Randomized, double-blind, placebo-controlled trial of monthly versus bimonthly dihydroartemisinin-piperaquine chemoprevention in adults at high risk of malaria
द्वारा: Lwin, K, और अन्य
प्रकाशित: (2012)