All-optical electrophysiology refines populations of in silico human iPSC-CMs for drug evaluation
High-throughput in vitro drug assays have been impacted by recent advances in human induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) technology and by contact-free all-optical systems simultaneously measuring action potentials (APs) and Ca2+ transients (CaTrs). Parallel computational a...
Main Authors: | , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2020
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