Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.

Several single-nucleotide polymorphisms (SNPs) have been associated with colorectal cancer (CRC) susceptibility. Most CRCs arise from adenomas, and SNPs therefore might affect predisposition to CRC by increasing adenoma risk. We found that 8 of 18 known CRC-associated SNPs (rs10936599, rs6983267, rs...

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Bibliographic Details
Main Authors: Carvajal-Carmona, L, Zauber, A, Jones, A, Howarth, K, Wang, J, Cheng, T, Riddell, R, Lanas, A, Morton, D, Bertagnolli, M, Tomlinson, I
Format: Journal article
Language:English
Published: 2013