Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.

Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.

Several single-nucleotide polymorphisms (SNPs) have been associated with colorectal cancer (CRC) susceptibility. Most CRCs arise from adenomas, and SNPs therefore might affect predisposition to CRC by increasing adenoma risk. We found that 8 of 18 known CRC-associated SNPs (rs10936599, rs6983267, rs...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Carvajal-Carmona, L, Zauber, A, Jones, A, Howarth, K, Wang, J, Cheng, T, Riddell, R, Lanas, A, Morton, D, Bertagnolli, M, Tomlinson, I
التنسيق:	Journal article
اللغة:	English
منشور في:	2013

مواد مشابهة

TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres
حسب: Jones, A, وآخرون
منشور في: (2012)

TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres.
حسب: Jones, A, وآخرون
منشور في: (2012)

Genetic Variants Associated with Colorectal Adenoma Susceptibility.
حسب: Anna Abulí, وآخرون
منشور في: (2016-01-01)

Homozygous PMS2 deletion causes a severe colorectal cancer and multiple adenoma phenotype without extraintestinal cancer.
حسب: Will, O, وآخرون
منشور في: (2007)

Fine Mapping of Colorectal Cancer Low Penetrance Susceptibility Loci
حسب: Carvajal-Carmona, L, وآخرون
منشور في: (2009)

Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas.
حسب: Fearnhead, N, وآخرون
منشور في: (2004)

Analysis of copy number changes suggests chromosomal instability in a minority of large colorectal adenomas.
حسب: Jones, A, وآخرون
منشور في: (2007)

APC mutations are sufficient for the growth of early colorectal adenomas.
حسب: Lamlum, H, وآخرون
منشور في: (2000)

Erratum: Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas (Nature Genetics (2013) 45 (136-144))
حسب: Palles, C, وآخرون
منشور في: (2013)

Bottom-up histogenesis of colorectal adenomas: origin in the monocryptal adenoma and initial expansion by crypt fission.
حسب: Preston, S, وآخرون
منشور في: (2003)

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas.
حسب: Palles, C, وآخرون
منشور في: (2013)

The spectrum of p53 mutations in colorectal adenomas differs from that in colorectal carcinomas.
حسب: Hao, X, وآخرون
منشور في: (2002)

Rare variant hypothesis for multifactorial inheritance: susceptibility to colorectal adenomas as a model.
حسب: Fearnhead, N, وآخرون
منشور في: (2005)

Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer.
حسب: Whiffin, N, وآخرون
منشور في: (2013)

The multiple colorectal adenoma phenotype and MYH, a base excision repair gene.
حسب: Lipton, L, وآخرون
منشور في: (2004)

Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas
حسب: Hansteen Inger-Lise, وآخرون
منشور في: (2007-12-01)

Regression of colorectal adenoma
حسب: Subin Song, وآخرون
منشور في: (2023-07-01)

Synchronous colorectal adenomas
حسب: Radovanović-Dinić Biljana, وآخرون
منشور في: (2010-01-01)

Inherited susceptibility to colorectal adenomas and carcinomas: evidence for a new predisposition gene on 15q14-q22.
حسب: Tomlinson, I, وآخرون
منشور في: (1999)

Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH/MUTYH mutations.
حسب: Thirlwell, C, وآخرون
منشور في: (2007)

A two-phase case-control study for colorectal cancer genetic susceptibility: candidate genes from chromosomal regions 9q22 and 3q22.
حسب: Abulí, A, وآخرون
منشور في: (2011)

A two-phase case-control study for colorectal cancer genetic susceptibility: candidate genes from chromosomal regions 9q22 and 3q22
حسب: Abulí, A, وآخرون
منشور في: (2011)

Fusobacterium is associated with colorectal adenomas.
حسب: Amber N McCoy, وآخرون
منشور في: (2013-01-01)

Adiposity factors are not related to the presence of colorectal adenomas
حسب: Chronis A, وآخرون
منشور في: (2011-11-01)

Frequency of germline hereditary non-polyposis colorectal cancer gene mutations in patients with multiple or early onset colorectal adenomas.
حسب: Beck, N, وآخرون
منشور في: (1997)

Evidence against a major genetic basis for combined breast and colorectal cancer susceptibility.
حسب: Brinkman, H, وآخرون
منشور في: (2006)

Association of plasma C-reactive protein level with the prevalence of colorectal adenoma: the Colorectal Adenoma Study in Tokyo
حسب: Nano Kigawa, وآخرون
منشور في: (2017-06-01)

Reduced expression of molecules of the cadherin/catenin complex in the transition from colorectal adenoma to carcinoma.
حسب: Hao, X, وآخرون
منشور في: (1997)

Top down or bottom up: competing management strategies in the histogenesis of colorectal adenomas
حسب: Wong, R, وآخرون
منشور في: (2002)

Pleomorphic adenoma parotid surgery, how much margin we can reach to be safe?
حسب: Saleh Mohebbi, وآخرون
منشور في: (2025-02-01)

Loss of expression and promoter methylation of SLIT2 are associated with sessile serrated adenoma formation
حسب: Beggs, A, وآخرون
منشور في: (2013)

DNA aneuploidy in colorectal adenomas: Role in the adenoma-carcinoma sequence Aneuploidía del ADN en adenomas colónicos: Papel en la secuencia adenoma-carcinoma
حسب: M. Alcántara Torres, وآخرون
منشور في: (2005-01-01)

Comprehensive mutation analysis in colorectal flat adenomas.
حسب: Quirinus J M Voorham, وآخرون
منشور في: (2012-01-01)

Presence of Iron in Colorectal Adenomas and Adenocarcinomas
منشور في: (2008-06-01)

Multiple colorectal adenomas in Lynch syndrome
حسب: Ayushi Jain, وآخرون
منشور في: (2022-12-01)

Age at menarche and risk of colorectal adenoma
حسب: Nam Hee Kim, وآخرون
منشور في: (2019-09-01)

Top down or bottom up morphogenesis of colorectal adenomas: Competing management structures in the origins of colorectal neoplasia
حسب: Preston, S, وآخرون
منشور في: (2003)

Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP.
حسب: Cheng, T, وآخرون
منشور في: (2014)

The Influence of the Genetic and Immunologic Context in the Development of Colorectal Adenoma: A Case Series Report
حسب: Diogo Garcia, وآخرون
منشور في: (2020-05-01)

Genetic pathways in colorectal cancer.
حسب: Ilyas, M, وآخرون
منشور في: (1996)